According to worlddownsyndromeday2.org, WDSD was first observed in 2006 in many countries around the world.
March 21 or 3-21 signifies the three copies of the 21st chromosome which is a genetic occurrence common in people with Trisomy 21, the most common form of Down syndrome
Thursday, mismatched socks also help raise awareness about Down syndrome. Organizations encourage everyone to wear brightly colored socks that signify the extra chromosome that people with Down syndrome usually carry.
Down syndrome is associated with distinct facial features, intellectual disabilities, developmental delays, and may be associated with thyroid or heart disease.
But many people with the disorder are able to lead productive lives. Most children with Down syndrome attend regular schools and 20 percent of adults are able to occupy paying jobs.
Down syndrome is diagnosed in 1 per 1,000 babies each year, resulting in approximately 200,000 new cases each year in the United States. More than 5 million people in the U.S. have Down syndrome.